摘要
4D打印技术可以通过增加时间维度,使打印出的三维模型在一定介质中随时间发生形变。该文由纤维素纳米纤维(NFC)、N,N-二甲基丙烯酰胺、光引发剂2959、葡萄糖氧化酶、葡萄糖和硅酸镁锂等制备出一种可以实现4D打印的复合支架墨水。该墨水具有受外界刺激响应的特性,打印出的图案在紫外光照下发生交联,从而使图形在水中随着时间发生特定形变。通过电镜观察墨水中水凝胶表面,并对其进行黏弹度和稳态剪切稀化的测试,结果表明:制备的水凝胶具有良好的交联性。同时将该支架墨水表面接种内皮细胞,培养7d后内生长状态良好,具有良好的生物相容性。
The 4 D printing technology can make the printed 3 D model deform with time in a certain medium by increasing the time dimension. In this paper, a composite scaffold ink for 4 D printing is prepared from cellulose nanofibers(NFC), N,N-dimethylacrylamide, photoinitiator 2959, glucose oxidase, glucose and magnesium lithium silicate. This ink has the property of responding to external stimuli, and the printed pattern is crosslinked under ultraviolet light, which makes the pattern deform with time in water. The surface of hydrogel in ink is observed by electron microscope and its viscoelasticity and steady state shear thinning are measured. The results show that the prepared hydrogel has good crosslinking property. At the same time, endothelial cells are seeded on the ink surface of the scaffold, which grow well within 7 days and have good biocompatibility.
作者
高志刚
罗勇
宋其玲
王世盛
GAO Zhigang;LUO Yong;SONG Qiling;WANG Shisheng(Chemical Engineering Comprehensive National Experimental Teaching Demonstration Center,School of Chemical Engineering,Dalian University of Technology,Dalian 116024,China)
出处
《实验技术与管理》
CAS
北大核心
2021年第4期57-60,65,共5页
Experimental Technology and Management
