新型冠状病毒肺炎疫情下居家隔离期间抽动障碍病儿病情影响因素分析

Analysis of influencing factors of children with tic disorder during isolation at home under the epidemic situation of Corona Virus Disease

目的探讨新型冠状病毒肺炎疫情下居家隔离期间抽动障碍病儿病情的影响因素,为临床治疗提供参考。方法以问卷形式,对2020年1月20日至3月21日广东省中医院214例抽动障碍病儿及监护人进行横断面调查,采用SPSS 23.0软件,对各相关因素进行单因素分析、多因素回归分析。结果病情反复组的监护人学历高、焦虑严重程度、不规律服药、学习压力比例均高于病情稳定组(大专及以上占比为62.9%比48.7%,中重度焦虑人数占比为25.8%比6.0%,不规律服药占比为68.0%比34.2%,学习压力占比为79.4%比38.5%;均P<0.05),病情反复组的课业负担时间、电子产品的使用≥4 h人数占比、YGTSS得分多于病情稳定组[4.5(2.5,6.5)h/d比3.5(2.0,5.5)h/d;73.2%比41.9%;21.0(13.0,32.0)比16.0(10.0,26.0);均P<0.05]。单因素分析显示监护人学历、焦虑严重程度、课业负担时间、学习压力、电子产品的使用、服药、YGTSS得分等均差异有统计学意义(P<0.05);采用向前逐步回归分析,结果显示:监护人焦虑程度、YGTSS得分、服药、电子产品使用、学习压力等5个因素差异有统计学意义(P<0.05)。结论监护人焦虑、YGTSS得分高、学习压力、电子产品使用、不规律服药是新型冠状病毒肺炎疫情下导致抽动障碍儿童病情加重的可能危险因素。

Objective To explore the influencing factors of children with tic disorder during isolation at home under the epidemic situation of Corona Virus Disease,and to provide reference basis for clinical practice.Methods A cross-sectional survey was conducted among 214 children with tic disorder in Guangdong Province Traditional Chinese Medical Hospital from January 20 to March 21,2020 and their guardians in the form of questionnaire.SPSS23.0 software was used to analyze the related factors by univariate analysis and multivariate regression analysis.Results The proportion of guardians with high education(College degree or above:62.9%vs.48.7%),anxiety severity(The number of moderate and severe anxiety:25.8%vs.6.0%),irregular medication(68,0%vs.34.2%)and learning pressure(79.4%vs.38.5%)in the recurrent group were higher than those in the stable group(all P<0.05).The burden time of schoolwork[4.5(2.5,6.5)h/d vs.3.5(2.0,5.5)h/d],the proportion of using electronic products≥4 hours[73.2%vs.41.9%]and the score of YGTSS[21.0(13.0,32.0)vs.16.0(10.0,26.0)]in the recurrent group were higher than those in the stable group(all P<0.05).Univariate analysis showed that there were significant differences in guardians’educational background,anxiety severity,time of schoolwork burden,learning pressure,use of electronic products,medication,and YGTSS score(P<0.05).The results of forward stepwise regression analysis showed that there were significant differences in guardians’anxiety,YGTSS score,medication,electronic product use and learning pressure(P<0.05).Conclusion Guardians’anxiety,high YGTSS score,learning pressure,use of electronic products and irregular medication are the possible risk factors leading to the aggravation of children with tic disorder under the epidemic situation.