脑小血管病与睡眠障碍相关性研究进展

Advances in the correlation between cerebral small vessel disease and sleep disorders

脑小血管病与睡眠障碍是老年人群中的两大常见疾病,关于二者的相关性尚未十分明确。不同类型睡眠障碍引起脑小血管病的机制不同。睡眠呼吸障碍是脑小血管病的重要危险因素;而非呼吸相关性睡眠障碍既可能增加脑小血管病的发病风险,也可能是脑小血管病引起的重要临床表现。本文根据睡眠障碍是否与呼吸相关,分别对脑小血管病与睡眠呼吸障碍、脑小血管病与非呼吸相关性睡眠障碍之间的相关性研究进行综述,以期提高对脑小血管病与睡眠障碍关系的认识,促进对脑小血管病的综合管理和干预研究。

In clinical practice,cerebral small vessel disease (CSVD) and sleep disorders are two common diseases in the elderly,the correlation between the two is not clear yet.Studies have found that different types of sleep disorders have different mechanisms for the occurrence and development of CSVD.Sleep-disordered breathing is a vital risk factor for CSVD.However,non-breathing-related sleep disorders may not only increase the risk of CSVD,but also be an important clinical manifestation of the disease.Based on whether sleep disorders are related to breathing or not,this article reviews the correlation between CSVD and sleep-disordered breathing,CSVD and non-breathing-related sleep disorders,respectively,to improve the understanding of the correlation between the two diseases,and to promote the comprehensive management and intervention research of CSVD.