摘要
An essential concept of cancer immunotherapy is that immunogenic cell death(ICD),characterized by the release of tumor-associated antigens(TAAs)and tumor-specific antigens(TSAs)like neoantigens,danger-associated molecular patterns(DAMPs),and pro-inflammatory cytokines,facilitates the presentation of TAAs and TSAs to adaptive immune cells,eliciting an emerging or reinstating a pre-existing anti-cancer immune response.
基金
The work was financially supported by the National Natural Science Foundation of China(Nos.81874233 and 51873207)
the Natural Science Foundation of Hubei Province(No.2019CFB465).