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拉贝洛尔联合硝苯地平治疗重症妊娠期高血压的效果及对妊娠结局的影响 被引量:4

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摘要 目的探讨拉贝洛尔联合硝苯地平治疗重症妊娠期高血压的效果及对妊娠结局的影响。方法将我院2018年2月至2020年3月接诊的94例重症妊娠期高血压患者按随机数字表法分为干预组、对照组,各47例。入院后两组均接受常规治疗,在此基础上,对照组口服硝苯地平,干预组行拉贝洛尔联合硝苯地平治疗。比较临床疗效、血压(舒张压、收缩压)、血管内皮功能〔内皮素-1(ET-1)、一氧化氮(NO)〕、妊娠结局。结果干预组治疗总有效率较对照组高,妊娠结局优于对照组,差异有统计学意义(P<0.05);干预组舒张压、收缩压、ET-1水平较对照组低,NO较对照组高,差异有统计学意义(P<0.05)。结论拉贝洛尔联合硝苯地平可有效控制重症妊娠期高血压患者的血压,利于改善血管内皮功能,降低剖宫产率和不良妊娠结局发生率。
作者 吴贵华
出处 《海峡药学》 2021年第5期150-152,共3页 Strait Pharmaceutical Journal
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