炎症性肠病对牙周病影响的研究进展

Research Progress of Effect of Inflammatory Bowel Disease on Periodontal Disease

炎症性肠病(inflammatory bowel disease,IBD)是肠道的慢性炎症性疾病,除了典型的肠内表现外,患者还可伴有多种口腔表现,其中牙周病受到越来越多的关注。IBD与牙周病在发病机制上存在相似性,均与局部微生物及免疫稳态失衡有关。因此,本文就IBD对牙周病影响的证据及可能机制做一综述。

Inflammatory bowel disease(IBD)is a chronic inflammatory disease of the gastrointestinal tract.Except for predominant bowel symptoms,patients may also have oral manifestations,of which periodontal disease has gained increasing attention.The pathogeneses of IBD and periodontal disease can both be related to disturbance of local microbial and immune homeostasis.Therefore,the purpose of this paper is to summarize the evidences and possible mechanisms of the effect IBD may have on periodontal disease.