摘要
Molecular determinants of SARS-CoV-2 replication fitness and sensitivity to neutralization via the humoral immune response critically inform efforts to combat the COVID-19 pandemic.Work published recently by Plante et al.in Nature highlights a key role for the D614G variant of the viral spike glycoprotein(S protein)in these processes.
基金
This work was supported by grants from the US National Institutes of Health(U24AI126683,P400D028116,and R24OD028257 to K.D.E.
R01AI052014 and R37AI039394 to A.N.E.).
