绵阳地区体检人群血栓弹力图检测结果分析

Analysis on the thromboelastography results of physical examination people in Mianyang

目的了解绵阳地区体检人群血栓弹力图(TEG)各参数水平及各参数的异常检出率。方法将2019年3月至9月于该院健康管理中心体检并行TEG检测者共3428例纳入研究。其中女性1650例、男性1778例,年龄22~91岁。所有体检者按年龄分为青年组(≤45岁)、中年组(46~59岁)、老年组(≥60岁)。采用YZ5000 TEG仪检测TEG参数,包括凝血反应时间(R)、凝血形成时间(K)、凝固角(α角)、最大振幅(MA)。比较不同性别以及不同年龄组间TEG各参数及各参数异常检出率的差异。结果与男性TEG参数比较,女性R、K缩短,α角、MA增大(P<0.05),女性R、α角异常检出率高于男性(P<0.05)。男性和女性比较,K、MA异常检出率差异无统计学意义(P>0.05)。男性体检者各年龄组间TEG参数差异有统计学意义(P<0.05),而TEG参数异常检出率差异无统计学意义(P>0.05)。女性体检者各年龄组间比较,K、α角、MA差异均有统计学意义(P<0.05),而TEG参数异常检出率比较,仅K异常检出率差异有统计学意义(P<0.05)。结论绵阳地区体检人群TEG参数存在明显的性别差异和一定程度的年龄差异。女性较男性处于更高的凝血状态,年龄对凝血状态也有一定程度影响。

Objective To investigate the levels of thromboelastometry(TEG)parameters and the abnormal detection rate of these parameters in the physical examination population in Mianyang.Methods A total of 3428 people who underwent physical examination and TEG test in the hospital from March 2019 to September 2019 were enrolled in the study,including 1778 males and 1650 females,aged 22 to 91 years old.According to the age,they were divided into young group(≤45 years old),middle-aged group(46-59 years old)and elderly group(≥60 years old).YZ5000 TEG instrument was used to detect the TEG parameters,such as reaction time(R),coagulation time(K)αangle and maximum amplitude(MA).The differences in the levels of TEG indicators and the abnormal detection rate of each indicator between different genders and different age groups were compared.Results Compared with male TEG parameters,female R and K were shortened,αangle and MA increased(P<0.05),and the abnormal detection rate of R andαangle in female was higher than that in male(P<0.05).There was no significant difference in the detection rate of abnormal K and MA between males and females(P>0.05).There were statistically significant differences in TEG parameters among the age groups of males(P<0.05),but there was no statistically significant difference in the detection rate of abnormal TEG parameters(P>0.05).There were statistically significant differences in K,αangle,MA among the age groups of females(P<0.05),while the abnormal detection rate of TEG parameters was compared,only the difference in K was statistically significant(P<0.05).Conclusion There are obvious gender differences and certain degree of age differences in the parameters of TEG in people who undergo physical examination in Mianyang.Females have higher coagulation status than males,meanwhile age also has a certain effect on coagulation status.