IgG4相关眼病三例

IgG4-related ophthalmic disease: three-case report

1例主诉为左眼视力下降1周;1例主诉为右眼视力减退2个月、结膜水肿10余天;1例主诉为双眼红肿1年,纳差、乏力4个月患者分别就诊眼科。3例患者均为男性,眼部检查均为双眼受累,2例表现为双眼泪腺肿大伴有球结膜水肿,1例为双眼眼睑肿胀,3例均伴有眶外组织受累,均诊断为IgG4相关眼病。经糖皮质激素冲击治疗后患者症状均好转,分别随访58、54、60个月,其中2例患者复发1次,1例患者复发3次。

The first patient complained visual loss of left eye for 1 week.The second patient complained visual loss of right eye for 2 months with conjunctival edema for more than 10 days.The third patient complained redness and swelling of both eyes for 1 year,poor appetite and fatigue for 4 months.All three patients were male with binocular involvement.Enlargement of lacrimal glands in both eyes with bulbar conjunctival edema were observed in 2 patients and binocular eyelid swelling in 1 patient,all 3 patients were associated with external orbital tissue involvement,which were diagnosed as IgG4-related ophthalmic diseases.After treatment with glucocorticoid,the symptoms of the patients were improved,and the patients were followed up for 58,54,and 60 months,respectively.Among the 3 patients,2 had recurrence for once,and 1 had recurrence 3 for times.