头孢曲松钠联合盐酸氨溴索治疗老年慢性支气管炎的效果研究

Effect of ceftriaxone sodium combined with ambroxol hydrochloride on chronic bronchitis in the elderly

目的:研究对老年慢性支气管炎患者采用头孢曲松钠联合盐酸氨溴索进行治疗的效果。方法:选择博罗县人民医院2018年1月至2020年2月收治的68例老年慢性支气管炎患者,根据入院的先后顺序将其分为头孢-氨溴索组和头孢曲松钠组(34例/组)。为头孢曲松钠组患者采用头孢曲松钠进行治疗,为头孢-氨溴索组患者采用头孢曲松钠联合盐酸氨溴索进行治疗,然后对比两组患者的临床疗效。结果:头孢-氨溴索组患者治疗的总有效率(94.11%)高于头孢曲松钠组患者治疗的总有效率(76.47%),P<0.05。治疗2周后,头孢-氨溴索组患者血清hs-CRP、PCT的水平均低于头孢曲松钠组患者,其FVC、FEV1及FEV1/FVC均高于头孢曲松钠组患者,P<0.05。结论:对老年慢性支气管炎患者采用头孢曲松钠联合盐酸氨溴索进行治疗的效果较为理想,能够有效地改善其肺功能,减轻其体内的炎症反应。

Objective:To study the effect of ceftriaxone sodium combined with ambroxol hydrochloride in the treatment of elderly patients with chronic bronchitis.METHODS:A total of 68 elderly patients with chronic bronchitis admitted to Boluo County People’s Hospital from January 2018 to February 2020 were selected and divided into cefo-ambroxol group and ceftriaxone sodium group(34 cases/group)according to the order of admission.Patients in the ceftriaxone sodium group were treated with ceftriaxone sodium,and patients in the cefa-ambroxol group were treated with ceftriaxone sodium combined with ambroxol hydrochloride,and then the clinical efficacy of the two groups was compared.RESULTS:The total effective rate of ceftriaxone group(94.11%)was higher than that of ceftriaxone sodium group(76.47%),P<0.05.After 2 weeks of treatment,serum hs-CRP and PCT levels in the ceftriaxone sodium group were lower than those in the ceftriaxone sodium group,and FVC,FEV1 and FEV1/FVC were higher than those in the ceftriaxone sodium group(P<0.05).Conclusion:Ceftriaxone sodium combined with ambroxol hydrochloride for the treatment of elderly patients with chronic bronchitis has an id eal effect,which can effectively improve the lung function and reduce the inflammatory response in vivo.