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缺血性脑卒中患者血清sdLDL-C、IL-17水平与斑块稳定性的关系分析 被引量:2

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摘要 目的探讨缺血性脑卒中(CIS)患者血清小而密低密度脂蛋白胆固醇(sdLDL-C)水平、白细胞介素17(IL-17)水平与斑块稳定性的关系。方法选择南方医科大学第三附属医院神经内科2018年1月~2019年1月收治的CIS患者216例,根据颈动脉多普勒彩色超声检测颈内动脉中层厚度(IMT),结果分为无斑块组45例、斑块组171例,根据斑块稳定性进一步细分为斑块稳定亚组82例和斑块不稳定亚组89例。用过氧化物酶法检测各组血清sdLDL-C、IL-17,分析比较检测结果,采用多变量logistic回归分析ACI不稳定型斑块形成的独立危险因素及血清sdLDL-C、IL-17水平与斑块稳定性的关系。结果稳定斑块亚组TC、sdLDLC、FBG、IL-1、IL-17水平均低于不稳定斑块亚组,差异均有统计学意义(P<0.05)。非条件多因素Logistic回归结果显示血清sdLDL-C、IL-17水平升高是斑块不稳定的独立危险因素(P<0.05)。结论CIS患者血清水平sdLDL-C、IL-17与斑块稳定性相关,sdLDL-C、IL-17水平的升高是斑块不稳定的独立预测因素。
出处 《现代诊断与治疗》 CAS 2021年第8期1271-1272,共2页 Modern Diagnosis and Treatment
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