复方蟾酥丸辅助治疗痈疖临床研究

Clinical Study on Compound Chansu Pills in Adjuvant Treatment of Carbuncle and Furuncle

目的:探讨复方蟾酥丸治疗痈疖溃疡的效果。方法:将痈、疖患者98例按随机数字表法分为对照组与观察组各49例。对照组应用常规西药治疗,观察组在对照组基础上联合复方蟾酥丸治疗。2组均连续治疗7 d,比较2组临床疗效,相关中医症状评分,血液实验室指标白细胞计数(WBC)、中性粒细胞比例(NEU%)水平及治疗过程中的不良反应情况。结果:2组总有效率均为100%,但2组间临床疗效比较,经秩和检验,差异有统计学意义(P<0.05),观察组疗效优于对照组。治疗前,2组病灶范围、颜色、肿胀、发热、疼痛等症状评分比较,差异均无统计学意义(P>0.05);治疗后,2组上述各项评分均较治疗前降低(P<0.05),且观察组各项评分均低于对照组(P<0.05)。治疗前,2组WBC、NEU%水平比较,差异无统计学意义(P>0.05);治疗后,2组WBC、NEU%水平较均治疗前降低(P<0.05),且观察组2项指标均低于对照组(P<0.05)。2组在治疗过程中均未发生任何严重药物不良反应。结论:复方蟾酥丸辅助西药治疗痈疖患者,可提高临床疗效,有效改善临床症状,且用药相对安全。

Objective:To discuss the effect of compound Chansu pills in adjuvant treatment of ulcer of carbuncle and furuncle.Methods:A total of 98 cases of patients divided into the control group and the observation group according to the random number table method,with 49 cases in each group.The control group was treated with western medicine,and the observation group was additionally treated with compound Chansu pills based on the treatment of the control group.Both groups were treated for seven days.The curative effect,the changes in related Chinese medicine symptom scores,the blood indexes including white blood cell count(WBC)and percentage of neutrophil(NEU%)and the adverse reactions during treatment in the two groups were compared.Results:The total effective rates were 100% in both groups,but the clinical effect between the two groups showed significant difference(P<0.05),and the curative effect in the observation group was better than that in the control group.Before treatment,there was no significant difference being found in the comparisons of scores of lesion range,color,swelling,fever,pain and other Chinese medicine symptoms between the two groups(P>0.05).After treatment,the above scores in the two groups were decreased when compared with those before treatment(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).Before treatment,there was no significant difference in the levels of WBC and neu% between the two groups(P>0.05).After treatment,the levels of WBC and neu% in the two groups were lower than before treatment(P<0.05),and the two indexes in the observation group were lower than those in the control group(P<0.05).During treatment,no serious adverse drug reactions occurred in both groups.Conclusion:Compound Chansu pills assisting western medicine for carbuncle and furuncle can improve the clinical efficacy and effectively improve the symptoms,with high medication safety.