早期连续性肾脏替代疗法辅助治疗重症肺炎合并急性肾损伤患者的效果分析

The effect of early continuous renal replacement therapy in the adjuvant treatment of patients with severe pneumonia and acute kidney injury

目的:研究早期连续性肾脏替代疗法(CRRT)辅助治疗重症肺炎合并急性肾损伤(AKI)患者的效果。方法:选择重症肺炎合并AKI的患者63例,根据治疗方式将其分为对照组(n=36)和研究组(n=27)。对照组进行常规治疗,研究组在对照组的基础上进行CRRT治疗。对比两组的肾功能、免疫功能情况。结果:治疗后研究组的尿氮素、血肌酐、血尿酸、C-反应蛋白低于对照组,中性粒细胞吞噬指数高于对照组,差异有统计学意义(P<0.05)。结论:CRRT辅助治疗重症肺炎合并AKI能够改善患者的肾功能及免疫功能,具有较高的应用价值。

Objective To study the effect of early continuous renal replacement therapy(CRRT)as an adjuvant treatment for patients with severe pneumonia and acute kidney injury(AKI).Method 63 patients with severe pneumonia and AKI in our hospital were selected and divided into the control group(36 cases)and the research group(27 cases)according to the treatment method.The control group received conventional treatment,and the research group received CRRT treatment based on the control group.Compare the renal function and immune function of the two groups.Results After treatment,the urinary nitrogen,blood creatinine,blood uric acid and C-reactive protein in the research group were lower than those in the control group(P<0.05),and the neutrophil phagocytic index was higher than that in the control group(P<0.05).Conclusion CRRT adjuvant treatment of severe pneumonia combined with AKI can improve the renal function and immune function of patients,and has high application value.