失效模式与效应分析在过敏性哮喘舌下脱敏治疗患儿中的应用价值

Application value of failure mode and effect analysis in sublingual desensitization treatment of children with allergic asthma

目的:探讨失效模式与效应分析(FMEA)在过敏性哮喘舌下脱敏治疗患儿中的应用价值。方法:126例过敏性哮喘患儿,根据不同的治疗方法将患儿分为观察组和对照组,每组各63例。对照组采用舌下脱敏治疗,观察组在对照组基础上加用FMEA以进行干预。随访1年,比较两组治疗依从性、治疗效果;干预前、干预1年后,评估患儿呼吸功能、过敏性哮喘疾病认知水平、生活质量。结果:观察组依从性优于对照组(P<0.05);治疗1年后,两组儿童哮喘控制测试量表(C-ACT)得分、第1秒呼气容积(FEV1)、用力呼气流量50%(FEF50%)、呼气峰流量(PEF)水平、主要照护者疾病认知水平、小儿哮喘生存质量问卷(PAQLQ)得分均高于治疗前(P<0.05);治疗后,观察组C-ACT得分、FEV1、FEF50%、主要照护者疾病认知水平、PAQLQ得分高于同期对照组(P<0.05)。结论:在过敏性哮喘舌下脱敏治疗中应用FMEA,能改善患儿依从性、临床疗效和生活质量,有一定的应用价值。

Objective:To explore the application value of failure mode and effect analysis(FMEA)in the treatment of sublingual desensitization in children with allergic asthma.Methods:126 children with allergic asthma were selected as the research objects,and they were divided into observation group and control group according to different treatment methods,63 cases in each group.The control group was treated with sublingual desensitization,and the observation group was intervened with FMEA on the basis of the control group.1 year follow-up was conducted to compare the treatment compliance and treatment effect of the two groups.Before and after the intervention,the respiratory function,cognitive level of allergic asthma and quality of life were evaluated.Results:The compliance of the observation group was better than that of the control group(P<0.05).After 1 year of treatment,the C-ACT scores,FEV1,FEF50%,PEF,the disease cognition level of the main caregivers and the PAQLQ scores of the observation group after treatment were higher than those before treatment(P<0.05).The C-ACT scores,FEV1,FEF50%,PEF,the disease cognition level of the main caregivers and the PAQLQ score of the observation group were higher than those of the control group at the same period(P<0.05).Conclusion:The application of FMEA in the treatment of sublingual desensitization of allergic asthma can improve the compliance,clinical efficacy and quality of life of children,which has a certain application value.