抗幽门螺杆菌治疗对冠心病疗效的分析

Analysis of Curative Effect of Anti-Helicobacter Pylori Therapy on Coronary Heart Disease

目的分析抗幽门螺杆菌治疗对冠心病的疗效。方法该研究选择2018年7月—2020年7月84例冠心病患者为研究对象,电脑随机分组,对照组、试验组各42例,分别行常规治疗、常规治疗+抗幽门螺杆菌治疗,分析疗效。结果试验组临床有效率92.86%显著高于对照组,差异有统计学意义(χ^(2)=5.486,P<0.05)。治疗后,两组三酰甘油(TG)、纤维蛋白原(FIB)及超敏C反应蛋白(hs-CRP)水平下降,试验组低于对照组,差异有统计学意义(t=15.258、9.088、2.103,P<0.05)。试验组不良事件发生率7.14%显著低于对照组,差异有统计学意义(χ^(2)=6.574,P<0.05)。治疗后,两组同型半胱胺酸(Hcy)水平下降,试验组Hcy水平低于对照组,差异有统计学意义(t=13.411,P<0.05)。结论抗幽门螺杆菌治疗冠心病疗效显著,可提高冠心病治疗效率,改善相关因子水平,减少不良事件。

Objective To analyze the efficacy of anti-Helicobacter pylori therapy on coronary heart disease.Methods The study selected 84 patients with coronary heart disease from July 2018 to July 2020 as the research objects.They were randomly grouped by computer,and 42 cases in the control group and the test group were treated with conventional treatment,conventional treatment+anti-Helicobacter pylori treatment,respectively,and the curative effect was analyzed.Results The clinical effective rate of 92.86%in the test group was significantly higher than that in the control group,the difference was statistically significant(χ^(2)=5.486,P<0.05).After treatment,the levels of triacylglycerol(TG),fibrinogen(FIB)and high sensitive C-reactive protein(hs-CRP)in the two groups decreased,and the test group was lower than the control group,and the difference was statistically significant(t=15.258,9.088,2.103,P<0.05).The incidence of adverse event of 7.14%in the test group was significantly lower than that in the control group,and the difference was statistically significant(χ^(2)=6.574,P<0.05).After treatment,the homocysteine(Hcy)level of the two groups decreased,and the Hcy level of the test group was lower than that of the control group,the difference was statistically significant(t=13.411,P<0.05).Conclusion Anti-Helicobacter pylori has a significant effect on the treatment of coronary heart disease,which can improve the treatment efficiency of coronary heart disease,improve the level of related factors,and reduce adverse events.