α_(1)受体阻滞剂联合抗菌药物治疗慢性前列腺炎的有效性探讨

Study on the Effectiveness of α_(1) Receptor Blocker Combined with Antibacterial Drugs in the Treatment of Chronic Prostatitis

目的对慢性前列腺炎采取α_(1)受体阻滞剂联合抗菌药物医治的有效性进行探讨。方法该次将2019年1月—2020年8月该院收治的慢性前列腺炎患者96例作为研究的对象,按随机数字表法分成两组,对照组48例采取抗菌药物治疗,观察组48例采取α_(1)受体阻滞剂联合抗菌药物治疗,进一步对比两组疗效。结果在慢性前列腺炎评分、最大尿道闭合压、最大尿道压、最大尿流率及平均尿流率方面,两组医治前均差异无统计学意义(t=0.169、1.204、0.653、-0.123、-0.098,P>0.05);经积极医治后,在慢性前列腺炎评分最大尿道闭合压、最大尿道压方面,观察组均显著要比对照组低,最大尿流率、平均尿流率则均显著要比对照组高,差异有统计学意义(t=-8.679、-22.611、-15.864、16.042、4.392,P<0.05)。观察组治疗总有效率为95.83%,显著高于对照组的79.17%,差异有统计学意义(χ^(2)=6.095,P<0.05)。结论在临床中,针对慢性前列腺炎患者,实施α_(1)受体阻滞剂联合抗菌药物医治的效果明显;具备推广及使用的价值。

Objective To explore the effectiveness ofα_(1) receptor blockers combined with antibacterial drugs in the treatment of chronic prostatitis.Methods This time,96 patients with chronic prostatitis admitted to the hospital from January 2019 to August 2020 were the subjects of the study.They were divided into two groups according to the random number table method.Among them,48 patients in the control group were treated with antibiotics,and the observation group of 48 case were treated withα_(1) receptor blocker combined with antibacterial drugs,and the efficacy of the two groups was further compared.Results In terms of chronic prostatitis score,maximum urethral pressure,maximum urethral pressure,maximum urinary flow rate and average urinary flow rate,there was no statistically significant difference between the two groups before treatment(t=0.169,1.204,0.653,-0.123,-0.098,P>0.05);After active treatment,the chronic prostatitis score,maximum urethral closure pressure and maximum urethral pressure of the observation group were significantly lower than those of the control group,and the maximum urinary flow rate,and average urinary flow rate were significantly higher than the control group,the difference was statistically significant(t=-8.679,-22.611,-15.864,16.042,4.392,P<0.05).The total effective rate of treatment in the observation group was 95.83%,which was significantly higher than 79.17%in the control group,the difference was statistically significant(χ^(2)=6.095,P<0.05).Conclusion In the clinic,for patients with chronic prostatitis,the effect of the treatment ofα_(1) receptor blockers combined with antibacterial drugs is obvious;it has the value of promotion and use.