脱细胞真皮基质在乳腺癌术后乳房重建中的应用进展

Application progress of acellular dermal matrix in breast reconstruction after breast cancer surgery

近年来,越来越多的乳腺癌患者选择进行术后乳房重建。假体或扩张器植入的乳房重建术是临床常用的术式之一。脱细胞真皮基质(ADM)辅助的乳房假体植入术已广泛应用于临床。ADM不仅为乳房下极提供良好的支撑,改善重建术后乳房的美观性,而且也能降低术后包膜挛缩的发生率。然而,ADM辅助的乳房假体植入术也存在术后感染和血清肿等并发症。本文将对ADM的发展、特性、优缺点、手术中的应用以及在乳腺癌术后乳房重建中的研究进展进行综述。

In recent years,more and more patients with breast cancer choose to undergo breast reconstruction after mastectomy.The implant-based reconstruction is the mostly used surgical method in breast reconstruction surgery.Acellular dermal matrix(ADM)-assisted breast prosthesis implantation has been widely used in clinical practice.ADM have advantages in setting breast contouring because it can build a well support,provide a better aesthetic outcome after breast reconstruction and decrease the risk of capsular contracture after implant insertion.However,postoperative complications following ADM insertion include infection,seroma and so on.Herein,this article reviews the development,characteristics,advantages and disadvantages,and clinical application of ADM as well as its advance in breast reconstruction with implants after breast cancer surgery.