摘要
Objective To predict the epitopes of the spike protein of 2019 novel coronavirus(2019-nCoV)and to analyze the mutation characteristics of this protein.Methods The gene sequences of 2019-nCoV was downloaded from GenBank and Global Initiative on Sharing All Influenza Data database(as of March 4,2020).ClustalW,MEGA 7.0,Immune Epitope Database and other software were used for predicting potential B lymphocyte and T lymphocyte epitopes of spike protein.
作者
LI Hu
李虎(Dept Infect Dis,Instit Viral Hepatitis,Key Lab,Molecular Biol Infect Dis,Chin Edu Ministry,2nd Affil Hosp,Chongqing Med Univ,Chongqing 400010)