水凝胶应用在关节损伤中的意义和进展

Research progress on the application of hydrogel in joint chronic sports injury

水凝胶是一种吸收大量水后可形成交联聚合物网络材料,具有优良的生物相容性和力学特性,水凝胶种类繁多,在人工关节置换、生物填充材料、药物缓释、组织工程等医学领域有较多的应用与值得开发的潜能。本文重点介绍了具备关节隔离支撑、药物长效释放以及用作组织工程支架等一系列水凝胶在关节慢性运动损伤的研究进展,详细阐述了兼具以上功能的水凝胶的性能、应用,并对水凝胶在关节损伤应用的研究现状及前景进行了讨论。

Hydrogel is a kind of cross⁃linked polymer network material that absorbs a large amount of water and has excellent biocompatibility and mechanical properties.There are many kinds of hydrogels,which have many applications and worth developing potential in medical fields such as artificial joint replacement,biological filling materials,drug sustained release and tissue engineering.This paper mainly introduces the long⁃term isolation have joint support,drug release and used as tissue engineering scaf⁃folds,and a series of hydrogel in joint research progress of chronic sports injuries,in detail elaborated the hydrogel with the function of the above properties,applications,and research on the application of the hydrogels in joint damage status quo and prospects are discussed.