脊髓电刺激治疗糖尿病性周围神经病的研究进展

Research progress of spinal cord stimulation in the treatment of diabetic peripheral neuropathy

糖尿病性周围神经病(DPN)是糖尿病常见慢性并发症,目前治疗方法有营养神经、活血化瘀等药物治疗以及肢体周围神经减压术等,但部分患者治疗效果欠佳。脊髓电刺激(SCS)作为一项神经调控技术,能够有效减轻DPN患者疼痛,扩张下肢周围血管、改善血运,改善患者生活质量,现已成为国内外研究的热点。本文就SCS用于治疗DPN的机制及进展作一综述,以期为临床治疗DPN提供新思路。

Diabetic peripheral neuropathy(DPN)is a common chronic complication of diabetes.At present,the treatment methods include drug therapy used to nourishing nerve and improving microcirculation,surgical method to decompressing peripheral nerve.But the treatment effect of some patients is not well.Spinal cord stimulation(SCS),as a new neuromodulation technique,can effectively relieve the pain of patients with DPN,dilate the peripheral blood vessels of lower limbs,improve blood supply,and improve the quality of life of patients.It is becoming a research hotspot.In this paper,the mechanism and progress of SCS in the treatment of DPN are described,in order to provide an effective alternative treatment for DPN patients.