依替米星联合哌拉西林配合护理干预治疗肺部感染的临床疗效

Clinical Efficacy of Etimicin Plus Piperacillin with Nursing Intervention in Pulmonary Infection

目的:研究依替米星联合哌拉西林配合护理干预用于治疗肺部感染患者的价值和临床疗效。方法:选取本院2018年2月~2020年1月纳入的104例肺部感染患者为研究对象,依照随机双盲法分为A组与B组。A组给予依替米星联合哌拉西林,B组给予依替米星治疗,每组52例。此外,给予相应的护理措施,干预后3个月对两组总有效率进行评价,同时记录所有受试者的体温恢复、咳嗽消退、肺部啰音消退、白细胞恢复、住院时长,观察腹泻、眩晕耳鸣、听力下降、肌酐与尿素氮水平升高等不良反应发生率,护理前后进行生活质量(SF-36)评分调查,对比两组干预效果。结果:A组的总有效率(88.46%)高于B组(71.15%,P<0.05);A组体温恢复、咳嗽消退、肺部啰音消退、白细胞恢复、住院时长均短于B组(P<0.05);A组不良反应发生率(5.77%)与B组(11.54%)比较无统计学差异(P>0.05)。干预前两组SF-36评分相比无统计学差异(P>0.05),干预后A组各评分高于对照组(P<0.05)。结论:依替米星联合哌拉西林用于肺部感染患者效果更为突出,同时提供对应的护理干预,可快速稳定病情、减少治疗时长,避免不必要的不良反应产生,为预后提供保障,提升患者生活质量。

Objective:To study the clinical value and efficacy of etimicin plus piperacillin with nursing intervention in pulmonary infection patients.Methods:A total of 104 pulmonary infection patients treated from February 2018 to January 2020 in our hospital were selected as research subject.Patients were divided into group A and group B according to random double-blind method.Group A was treated with etimicin plus piperacillin,Group B was treated with etimicin,52 cases in each group.In addition,appropriate nursing measures were provided.After 3 months of interventions,total effective rate of the two groups were evaluated as well as time of body temperature recovery,cough disappearance,lung rale disappearance,white blood cell recovery and hospitalization were recorded;the incidences of adverse reactions like diarrhea,dizziness,tinnitus,hearing loss,the increased level of creatinine and urea nitrogen were observed;quality of life(SF-36)scores before and after nursing were investigated.The intervention effect of the two groups was compared.Results:Total effective rate in group A(88.46%)was significantly higher than group B(71.15%,P<0.05);time of body temperature recovery,cough disappearance,lung rale disappearance,white blood cell recovery and hospitalization in group A was significantly shorter than group B(P<0.05).There was no significantly different in adverse effects rate between group A(5.77%)and group B(11.54%,P>0.05).There was no significant difference in SF-36 scores between the two groups before intervention(P>0.05),but the scores in group A were higher than those in the control group after intervention(P<0.05).Conclusion:The effect of etimicin combined with piperacillin in patients with pulmonary infection is more prominent,which can stabilize the illness state,reduce the treatment time,avoid unnecessary adverse reactions,provide a guarantee for the prognosis,and improve the quality of life,with corresponding nursing intervention at the same time.