温针灸配合推拿手法对慢性盆腔炎患者血液流变学及炎症因子的影响

Effect of warming acupuncture moxibustion combined with Tuina manipulation on hemorheology and inflammatory factors in patients with chronic pelvic inflammatory disease

目的探究温针灸配合推拿手法对慢性盆腔炎患者血液流变学及炎症因子的影响。方法选取2019年1~12月商洛市妇幼保健院收治的100例慢性盆腔炎患者为研究对象,采用随机数表法分为对照组和观察组,每组50例。对照组予以西医基础治疗,观察组在对照组治疗的基础上增加温针灸配合推拿手法治疗,两组均持续治疗1周。于治疗后比较两组患者的临床治疗效果,以及治疗前后的中医证候积分、血液流变学指标[全血黏度(b)、血浆黏度(hp)、红细胞聚集指数(AI)、纤维蛋白原(Fib)]、血清炎症因子[白细胞介素-6(IL-6)、C反应蛋白(CRP)、转化生长因子-β_(1)(TGF-β_(1))]水平。结果观察组患者的临床治疗总有效率为90.0%,明显高于对照组的74.0%,差异有统计学意义(P<0.05);治疗后,观察组患者的中医证候积分为(8.65±1.26)分,明显低于对照组的(10.68±1.35)分,差异有统计学意义(P<0.05);治疗后,观察组和对照组患者的b[(3.37±0.19)mPa/s vs(3.52±0.23)mPa/s]、hp[(1.36±0.25)mPa/s vs(1.55±0.31)mPa/s]、AI[(4.43±1.16)vs(4.93±1.22)]、Fib[(2.91±0.52)g/L vs(3.34±0.58)g/L]及血清IL-6[(0.98±0.31)mg/L vs(1.25±0.34)mg/L]、CRP[(4.24±1.03)mg/L vs(6.23±1.10)mg/L]比较,观察组较对照组更低,血清TGF-β_(1)[(26.28±3.75)mg/L vs(22.97±3.46)mg/L]比较,观察组较对照组更高,差异均具有统计学意义(P<0.05)。结论温针灸配合推拿手法可有效缓解慢性盆腔炎患者的临床症状,改善血液流变学,减轻炎症反应,临床治疗效果较好。

Objective To explore the effects of warming acupuncture moxibustion combined with Tuina manipulation on hemorheology and inflammatory factors in patients with chronic pelvic inflammatory disease.Methods A total of 100 patients with chronic pelvic inflammatory disease admitted to the Shangluo Maternal and Child Health Hospital from January 2019 to December 2019 were selected as the research objects.They were randomly divided into a control group and an observation group by random number table method,with 50 cases in each group.The control group was given basic treatment of western medicine,and the observation group was given warming acupuncture moxibustion combined with Tuina manipulation on the basis of the treatment of the control group.Both groups received treatment for 1 week.After treatment,the clinical therapeutic effects were compared between the two groups,as well as these indicators before and after treatment,such as TCM syndrome scores,hemorheological indexes(whole blood viscosity[b],plasma viscosity[hp],red blood cell aggregation index[AI],fibrinogen[Fib]),and the levels of serum inflammatory factors[Interleukin-6[IL-6],C-reactive protein[CRP],transforming growth factor-β_(1)[TGF-β_(1)]).Results The total effective rate of clinical treatment in the observation group was 90.0%,which was significantly higher than 74.0%in the control group(P<0.05).After treatment,the TCM syndrome score was(8.65±1.26)points in the observation group,which was significantly lower than(10.68±1.35)points in the control group(P<0.05).After treatment,the b,hp,AI,Fib,serum IL-6,and CRP were compared between the observation group and the control group.The data were as follow:b(3.37±0.19)mPa/s vs(3.52±0.23)mPa/s,hp(1.36±0.5)mPa/s vs(1.55±0.31)mPa/s,AI(4.43±1.16)vs(4.93±1.22),Fib(2.91±0.52)g/L vs(3.34±0.58)g/L,serum IL-6(0.98±0.31)mg/L vs(1.25±0.34)mg/L,CRP(4.24±1.03)mg/L vs(6.23±1.10)mg/L,and these results were all lower in the observation group than in the control group;while serum TGF-β_(1) were higher in the observation group than in the control group:(26.28±3.75)mg/L vs(22.97±3.46)mg/L,P<0.05.Conclusion Warming acupuncture moxibustion combined with Tuina manipulation can effectively relieve the clinical symptoms of patients with chronic pelvic inflammatory disease,improve hemorheology,reduce inflammatory,and have a better clinical treatment effect.