摘要
射血分数保留性心力衰竭(HFpEF)患病率逐年上升,渐渐成为心力衰竭研究的热点,将其以亚群分类进行研究探讨是目前的主流趋势。其中,2型糖尿病(T2DM)目前仍然是HFpEF最普遍的危险因素之一,理解二者间的关系对于HFpEF的预防、治疗及预后评估具有重要意义。文章阐述糖尿病对HFpEF患者的影响,探索T2DM相关HFpEF的可能病理生理机制,并对近年的相关新型药物治疗进行综述。
The prevalence of heart failure with preserved ejection fraction(HFpEF)has been increasing year by year,and has gradually become a hot spot in the research of heart failure.It is the current mainstream trend to research and discuss it in subgroups.Among them,type 2 diabetes(T2DM)is still one of the most common risk factors for HFpEF.Understanding the relationship between the two is of great significance for the prevention,treatment and prognosis evaluation of HFpEF.This article describes the impact of diabetes on HFpEF patients,explores the possible pathophysiological mechanism of T2DM-related HFpEF,and reviews related new drug treatments in recent years.
作者
李畅(综述)
栾天竹(审校)
Li Chang;Luan Tianzhu(Department of Cardiology, the First Affiliated Hospital of Harbin Medical University, Heilongjiang Province,Harbin 150000,China)
出处
《疑难病杂志》
CAS
2021年第6期631-635,共5页
Chinese Journal of Difficult and Complicated Cases
关键词
射血分数保留性心力衰竭
糖尿病
2型
病理生理机制
药物治疗
Heart failure with preserved ejection fraction
Diabetes mellitus,type 2
Pathophysiological mechanism
Medication treatment
