针刺治疗坐骨神经痛脑功能磁共振研究进展

Progress of Study on fMRI in Sciatica Treated by Acupuncture

针刺治疗坐骨神经痛在临床应用广泛,但其具体作用机制尚不确切。应用功能磁共振成像(Bold-fMRI)技术可以从影像学角度为针刺治疗坐骨神经疼痛提供客观理论依据,进而对针刺治疗坐骨神经痛的中枢机制进行分析与探索。本文对比针刺治疗坐骨神经痛任务态和静息态fMRI相关研究文献进行综述,发现针刺镇痛主要引起与痛觉辨识、疼痛认知、情绪调控有关脑区的神经元活动发生改变。以期为后续研究针刺镇痛的脑响应机制提供参考。

Acupuncture is widely used in the treatment of sciatica,but its specific mechanism is not accurate.The application of Bold-fMRI can provide objective theoretical basis for acupuncture treatment of sciatic nerve pain from the perspective of imaging,and then analyze and explore the central mechanism of acupuncture in the treatment of sciatica.This paper compares the literature of fMRI in the task-state and rest-state of sciatica treated by acupuncture.It is found that acupuncture analgesia mainly causes the changes of neuron activity in brain area related to pain recognition,pain cognition and emotional regulation.