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细菌性阴道炎实施乳酸杆菌治疗对其恢复阴道微生态环境的作用 被引量:2

Effect of Lactobacillus Treatment on Bacterial Vaginitis Restoring the Vaginal Microecological Environment
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摘要 目的:评定细菌性阴道炎患者选用乳酸杆菌用药治疗方式对恢复其阴道相关微生态环境形成的作用状况。方法:课题指标来自于2019年5月—2020年5月本医院实施用药治疗的100例细菌性阴道炎患者详细评估资料,实施组别分组方式选用随机数字表方法,各个组别入组例数50例,试验组采取基础抗菌用药加乳酸杆菌用药方法,参照组采取基础抗菌用药方法,研究各个组别用药方面治疗所得效果有效统计值、阴道乳酸杆菌数目恢复正常所占比例数、用药治疗之后三个月中出现复发所占比例数、对于用药治疗得到结果满意所占比例数,分析各个组别开展用药治疗之前和开展用药治疗10天之后阴道pH检测值具体状况、阴道对应菌群密集程度具体分级情况。结果:试验组用药方面治疗所得效果有效统计值对比参照组详细评定数值内容呈现提升(P<0.05);各个组别开展用药治疗之前阴道pH检测值大于4.5所占比例数对比差距情况较小(P>0.05),试验组开展用药治疗10天之后阴道pH检测值大于4.5所占比例数对比参照组详细评定数值内容呈现下降(P<0.05);各个组别开展用药治疗之前阴道对应菌群密集程度分级Ⅱ级及Ⅲ级所占比例数对比差距情况较小(P>0.05),试验组开展用药治疗10天之后阴道对应菌群密集程度分级Ⅱ级及Ⅲ级所占比例数对比参照组详细评定数值内容呈现提升(P<0.05);试验组阴道乳酸杆菌数目恢复正常所占比例数对比参照组详细评定数值内容呈现提升(P<0.05);试验组用药治疗之后三个月中出现复发所占比例数对比参照组详细评定数值内容呈现下降(P<0.05);试验组对于用药治疗得到结果满意所占比例数对比参照组详细评定数值内容呈现提升(P<0.05)。结论:为细菌性阴道炎患者提供乳酸杆菌用药治疗方式有助于促进其阴道相关微生态环境得以恢复。 Objective:To evaluate the effect of Lactobacillus treatment on patients with bacterial vaginitis in restoring the formation of vaginal micro-ecological environment.Method:The subject indicators come from the detailed evaluation data of 100 patients with bacterial vaginitis who were treated with medications in our hospital from May 2019 to May 2020.The random number table method was selected for group grouping,and each group was included in the group.There are 50 cases.The test group adopts basic antibacterial medication plus Lactobacillus medication,and the reference group adopts basic antibacterial medication to study the effective statistics of the treatment effects of medication in each group,the percentage of the vaginal lactobacillus number returning to normal,and medication treatment The proportion of recurrence in the next three months,the proportion of satisfaction with the results of the medication treatment,and the analysis of the specific status of the vaginal pH detection value of each group before the medication treatment and 10 days after the medication treatment,and the dense vaginal flora The degree of specific classification.Results:The effective statistical value of the treatment effect of the test group was improved compared with the detailed evaluation value of the reference group(P<0.05);the vaginal pH test value of each group was greater than 4.5 before the drug treatment,and the difference in the proportion of the number of comparisons was small(P>0.05),the percentage of the vaginal pH test value greater than 4.5 after 10 days of drug treatment in the test group showed a decrease compared with the detailed evaluation value of the reference group(P<0.05);the corresponding vaginal flora of each group was dense before drug treatment The difference between the proportions occupied by grade Ⅱ and grade Ⅲ is relatively small(P>0.05).After 10 days of drug treatment in the test group,the corresponding vaginal flora density grading grade Ⅱ and grade Ⅲ occupy the proportion of the reference group.Details The content of the evaluation value showed an increase(P<0.05);the proportion of the number of vaginal lactobacilli in the test group returned to normal was increased compared with the detailed evaluation value of the reference group(P<0.05);the test group had recurrence within three months after treatment Compared with the reference group,the proportion of the detailed evaluation value content decreased(P<0.05);the proportion of the test group that was satisfied with the results of the medication treatment showed an increase compared with the reference group's detailed evaluation value content(P<0.05).Conclusion:Providing Lactobacillus medication for patients with bacterial vaginitis helps to promote the restoration of the vagina-related micro-ecological environment.
作者 王嘉贤 刘北梅 陈佩仪 Wang Jiaxian(Department of Gynecology,Dalang Hospital,Dongguan City,Dongguan Guangdong 523770)
出处 《黑龙江医药》 CAS 2021年第3期511-515,共5页 Heilongjiang Medicine journal
基金 东莞市社会科技发展项目(编号:201950715040819)。
关键词 细菌性阴道炎 乳酸杆菌 阴道 微生态环境 bacterial vaginitis lactobacillus vagina microecological environment
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