卵圆孔未闭与偏头痛的相关性研究进展

Research Progress on the Relationship between Patent Foramen Ovale and Migraine

偏头痛是一种慢性血管性疾病,多表现为单侧、搏动性、中重度头痛发作,常伴恶心呕吐、畏光畏声等,中年女性高发,由于其较高的致残性且发病机制不明,一直以来被业内研究者所关注,并提出了许多假说。近年研究提示,发现卵圆孔未闭在偏头痛患者中的存在率远远高于健康人群,两者之间存在一定的相关性,通过关闭未闭合的卵圆孔,部分偏头痛患者症状得以缓解。文中对偏头痛与卵圆孔未闭之间相关性研究进展进行综述。

Migraine is a chronic vascular diseases,with the clinical feature of unilateral,pulsatility,moderate to severe headache,often accompanied by nausea and vomiting,photophobia,phonophobia,and so on,which most happened in middle-aged women.Because of its high disability and unknown pathogenesis,it has been concerned by researchers and put forward many hypotheses.Recent studies have found that the rate of patent foramen ovale in migraine patients is much higher than that in healthy people,and there is a certain correlation between them.The symptoms of migraine patients can be relieved by closing patent foramen ovale.The research progress between migraine and patent foramen ovale were reviewed.