左氧氟沙星致重度药源性血小板减少症的药学监护

Pharmaceutical Care for Severe Drug-Induced Thrombocytopenia Induced by Levofloxacin

目的:探索左氧氟沙星致重度药源性血小板减少症的药学监护要点。方法:临床药师对发生重度药源性血小板减少症的患者进行用药分析及监护,认为血小板减少症最有可能由左氧氟沙星氯化钠注射液引起,建议医师立即停止使用该药,医师采纳建议并停用左氧氟沙星氯化钠注射液。结果:通过停止使用左氧氟沙星,同时进行升血小板、补充凝血因子的治疗,最终患者病情好转。结论:临床药师通过对患者进行药学监护,可以提高临床用药安全性。

OBJECTIVE:To probe into the key points of pharmaceutical care for severe drug-induced thrombocytopenia induced by levofloxacin.METHODS:Clinical pharmacists performed medication analysis and monitoring on patients with severe drug-induced thrombocytopenia,and concluded that thrombocytopenia was most likely induced by levofloxacin sodium chloride injection,the clinicians were advised to stop using the drugs.The clinicians adopted the recommendation and discontinued levofloxacin sodium chloride injection.RESULTS:By discontinuing levofloxacin,along with platelet enhancement and coagulation factor supplement,the condition of the patient eventually improved.CONCLUSIONS:Clinical pharmacists can improve the safety of clinical medication by providing pharmaceutical care for patients.