低血糖对糖尿病患者认知功能障碍影响的研究新进展

New progress in the effect of hypoglycemia on cognitive dysfunction in diabetic patients

低血糖在糖尿病患者的日常血糖管理中很常见,越来越多的研究认为低血糖在认知功能障碍的发病机制中起到重要作用。严重的低血糖与认知功能障碍可能存在双向关系,造成低血糖与认知功能障碍互为加重的恶性循环后果,但具体的作用机制尚未明确。本文就低血糖与认知功能障碍的关系、低血糖致认知功能障碍的机制、临床管理措施等内容进行综述,以期提高对低血糖与认知功能障碍关系的认识,为深入探讨糖尿病合并认知功能障碍的机制提供科学依据。

Hypoglycemia is very common in daily blood glucose management of diabetic patients,and growing number of studies have proved that hypoglycemia plays an important role in the pathogenesis of cognitive dysfunction.There may be a bidirectional relationship between severe hypoglycemia and cognitive dysfunction,resulting in a vicious circle of mutual aggravation between hypoglycemia and cognitive dysfunction,but the specific mechanism is not clear.This article reviews the relationship between hypoglycemia and cognitive dysfunction,the mechanism of hypoglycemia induced cognitive dysfunction,and clinical management measures.The aim is to improve the understanding of the relationship between hypoglycemia and cognitive dysfunction,and to provide scientific basis for further exploring the mechanism of diabetes mellitus with cognitive dysfunction.