我国环境污染与健康基础研究的若干新需求

New Demands in Basic Research on Environmental Pollution and Health in China

良好的生态环境是建设世界科技强国的重要保障。我国目前面临复杂的环境污染形势,虽然近年来的污染控制卓有成效,但环境污染的毒性效应造成的急性或慢性疾病高发风险不容忽视。目前,我国许多区域性疾病高发的环境污染诱因尚不明确。解决这些环境健康问题亟待开展多学科协同的基础研究,建立“污染过程—人体暴露—人体响应—疾病发生”的全局研究路线,争取在暴露组学、超痕量测量与溯源方法学、分子流行病学、环境大数据和人工智能等交叉领域取得突破,实现健康风险导向的精准污染防控。

The complex environmental pollution in China greatly threatens the human health.Although the pollution control policies have taken a great effect in recent years,the resultant long-term,chronic health risks are still concerned.Until now,the causes of many regional high-incidence diseases are still unclear.In order to solve these environmental health problems,we need multi-disciplinary innovations in basic research to establish the comprehensive research chain of“pollution process–human exposure–body response–disease development”.We need breakthroughs in interdisciplinary fields including exposomics,ultratrace measurement and source tracing methodology,molecular epidemiology,environmental big data,and artificial intelligence.Only in this way can we achieve the health risk-oriented precise prevention and control of environmental pollution.