质量标志物(Q-Marker)预测分析途径研究进展

Research progress on prediction and analysis approaches of quality markers(Q-Marker)

为不断完善我国中药产品质量标准体系以及现有的评价质量方法,刘昌孝院士首次提出了质量标志物(quality marker,Q-Marker)的概念。众多学者根据Q-Marker所应该满足的五原则而预测中药材的Q-Marker,现通过对大黄、人参、茯苓等20味中药材依据不同的途径预测出的不同的Q-Marker研究成果进行总结,以期对相关研究提供参考。

Objective In order to continuously improve the drug quality standard system in China and the existing quality evaluation methods,AcademicianChangxiaoLiu proposed the concept of quality marker Q-Marker for the first time.Many scholars predicted the Q-markers of Chinese medicinal materials according to the five principles that should be met by Q-markers.This paper summarized the different research results of Q-markers of 20 Chinese medicinal materials,such as Dahuang(Rhei Radix et Rhizoma),Renshen(Ginseng Radix et Rhizoma)and Fuling(Poria),which were predicted according to different ways,in order to provide reference for related research.