肠道菌群与缺血性卒中

Intestinal flora and ischemic stroke

脑肠轴是中枢神经系统与胃肠道间相互作用的重要通路。缺血性卒中可促进肠道菌群失调和移位,肠道菌群及其代谢产物也会反向影响缺血性卒中的发生、发展及转归。文章对缺血性卒中与肠道菌群的相关文献进行回顾,以综述两者的联系及相关机制,并对靶向肠道菌群的卒中治疗进行了展望。

The brain-gut axis is an important pathway for the interaction between the central nervous system and the gastrointestinal tract.Ischemic stroke can promote the imbalance and displacement of intestinal flora,and the intestinal flora and its metabolites in turn can affect the occurrence,development and outcome of ischemic stroke.This article reviews the related literature on ischemic stroke and intestinal flora,in order to review the relationship between the two and related mechanisms,and to prospect the stroke treatment of targeting intestinal flora.