摘要
淋巴瘤是起源于身体不同部位以及具有多种病理亚型的血液系统恶性肿瘤。传统使用的评价指标为最大标准化摄取值,其反映肿瘤组织中的最大活性代谢程度,是目前临床研究应用最多的代谢参数。PET体积计算机辅助判读(VCAR)软件可对淋巴瘤病灶进行测量分析,自动计算病灶的代谢评估指标,包括瘦体标准化摄取值峰值、肿瘤代谢体积和病灶糖酵解总量等。但淋巴瘤病理亚型分类繁多,上述代谢评估参数对不同亚型淋巴瘤的诊断和疗效评估效率各不相同。因此,笔者对基于18F-氟脱氧葡萄糖PET VCAR软件有效预测淋巴瘤诊疗效能的最新进展进行综述。
Lymphoma is a malignant tumor of the hematological system that originates from different sites of the body and has a variety of pathological types.Maximum standardized uptake value,a traditionally used evaluation index,can reflect the maximum metabolic activity in tumor tissues,and which is the most widely studied metabolic parameter in clinical research at present.PET volume computed assisted reading(VCAR)software can measure and analyze the lymphoma lesions and automatically calculate the metabolic evaluation indexes of the lesions,including the peak SUV normalized by lean body mass,metabolic tumor volume,total lesion glycolysis,etc.There are many pathological subtypes of lymphoma,and the above metabolic evaluation parameters have different diagnosis and efficacy evaluation efficiency for different types of lymphoma.Therefore,the author intends to review recent advances in the effective prediction of the diagnostic and therapeutic effect of lymphoma based on the metabolic assessment of 18F-fluorodeoxyglucose PET VCAR software.
作者
苏玉林
王梓延
宋姝
朱高红
Su Yulin;Wang Ziyan;Song Shu;Zhu Gaohong(Department of Nuclear Medicine,the First Affiliated Hospital of Kunming Medical University,Kunming 650032,China)
出处
《国际放射医学核医学杂志》
2021年第3期187-191,共5页
International Journal of Radiation Medicine and Nuclear Medicine
基金
国家自然科学基金(81360223、81860313)
云南省高级医学领军人才项目(L-2017003)
昆明医科大学研究生创新基金(2019S114)。
