2009—2015年甘肃省肿瘤登记地区甲状腺癌流行特征及变化趋势

Epidemiological characteristics and trends of thyroid cancer in cancer registration areas of Gansu province,2009—2015

目的分析甘肃省肿瘤登记地区2009—2015年甲状腺癌发病与死亡的流行状况。方法审核整理2009—2015年甘肃省肿瘤登记地区甲状腺癌发病(死亡)例数、发病(死亡)率、构成比、中标率、世标率等,分析年龄别发病、死亡情况,并通过Jointpoint回归模型计算年度变化百分比(Annual percentage change,APC)进行时间趋势分析。结果甘肃省2009—2015年肿瘤登记地区甲状腺癌报告发病1087例,发病率为2.87/10万,中标率为2.51/10万;死亡率为0.86/10万,中标率0.80/10万;发病率和死亡率为女性高于男性,农村高于城市的特征;发病率和死亡率随年龄增长而增加;2009—2015年甲状腺癌中标发病率及死亡率均呈现上升趋势(APC=10.6%,t=2.4,P=0.10;APC=7.0%,t=1.3,P=0.30),趋势变化无统计学意义。结论2009—2015年甘肃省甲状腺癌症发病率和死亡率呈现较高水平,城市50岁以上女性是甲状腺癌防控的重点对象。

Objective To analyze the prevalence and mortality of thyroid cancer in cancer registration areas of Gansu province from 2009 to 2015.Methods The cases of incidence(mortality),proportion,ASR China and ASR World of thyroid cancer in cancer registration areas of Gansu province from 2009 to 2015 were reviewed and summarized,and the incidence and mortality of thyroid cancer by age were analyzed.Joinpoint regression model was used to calculate annual percentage change(APC)for time trend analysis.Results There were 1087 cases of thyroid cancer reported in Gansu cancer registration areas from 2009 to 2015,the incidence was 2.87/100000 and the ASR China was 2.51/100000.The mortality was 0.86/100000,and the ASR China was 0.80/100000.The incidence and mortality rates were higher in females than those of males and those of rural areas than in urban areas.Incidence and mortality increase with age;The incidence and mortality of thyroid cancer showed an increasing trend from 2009 to 2015(APC=10.6%,t=2.4,P=0.10;APC=7.0%,t=1.3,P=0.30),the change trend was not statistically significant.Conclusion The incidence and mortality of thyroid cancer in Gansu province were relatively high from 2009 to 2015,and women over 50 years old in urban areas were the key targets for thyroid cancer prevention and control.