判别分析法分析儿童喘息性疾病的临床表现

Analysis on the clinical manifestations of children with asthmatic diseases according to the discriminant analysis method

目的用判别分析法分析儿童喘息性疾病的临床表现,使其形成更为有意义的鉴别方式。方法收集在泰安市儿童医院儿科病房住院(2017年6月至2019年6月)并诊断为毛细支气管炎、喘息性支气管炎以及支气管哮喘的680例患儿的发病原因、临床表现、影像学X线片与实验室及其他相关辅助检查、治疗与转归等多种资料,进行整理、汇总和统计学分析。结果对三组疾病的临床表现进行判别分析,建立判别函数及模型,便于临床鉴别诊断。纳入判别函数的指标是湿啰音、年龄、气促、IgE、CRP、RSV,且差异有统计学意义(P<0.001)。经判别分析,提取出2个维度的典型判别函数,其中第1个函数解释所有变异的88%,剩下的12%的变异则由第2个判别函数来解释。结论儿童喘息性疾病的判别分析中,湿啰音、年龄、气促、IgE、CRP、RSV六个指标具有重要的鉴别诊断价值。

Objective To explore the clinical manifestations of children with asthmatic diseases according to the discriminant analysis method,so as to make it form a more meaningful way of identification.Methods The etiology,clinical manifestation,imaging X-ray film and laboratory and other related auxiliary examination,treatment and prognosis,etc.,of 680 children hospitalized in Pediatric Ward of Tai′an Maternal and Child Health Hospital from June 2017 to June 2019 who were diagnosed as bronchiolitis,asthmatic bronchitis and bronchial asthma were collected,sorted,summarized and statistically analyzed.Results The clinical manifestations of the three groups of diseases were analyzed according to the discriminant analysis method,and the discriminant function and model were established for clinical differential diagnosis.The indexes included in the discriminant function were wet rales,age,shortness of breath,IgE,CRP and RSV,all with statistically significant differences(P<0.001).After discriminant analysis,the typical discriminant functions of two dimensions were extracted,in which the first function explained 88%of all the variations,and the remaining 12%of the variations were explained by the second discriminant function.Conclusion In the discriminant analysis of children with asthmatic diseases,six indexes of wet rales,ages,shortness of breath,IgE,CRP and RSV,have important differential diagnostic value.