生殖道感染类型分布及其对女性血清炎症因子、性功能和心理状态的影响

Distribution of Reproductive Tract Infection Types and Its Influence on Serum Inflammatory Factors, Sexual Function and Psychological State in Women

目的:了解女性生殖道感染类型分布情况,分析生殖道感染对女性血清炎症因子、性功能和心理状态的影响。方法:选择2016年5月2018年8月到我院就诊的生殖道感染女性患者60例(研究组),另选取同期到我院进行健康体检的健康女性60例(对照组)。统计研究组患者生殖道感染的感染类型,并比较两组血清炎症因子、性功能和心理状态情况。结果:60例生殖道感染患者感染类型以宫颈炎(33.33%)、非特异性阴道炎(26.67%)居多。研究组血清肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)以及白细胞介素-8 (IL-8)水平分别为(144.38±31.85)ng/mL、(73.85±15.73)ng/mL、(218.64±43.28)ng/mL,均高于对照组的(99.01±22.25)ng/mL、(40.27±10.52)ng/mL、(113.82±26.08)ng/mL,差异有统计学意义(均P<0.05)。研究组性欲、高潮频数、性满意度、性焦虑、配偶高潮频数、配偶性满意度评分分别为(3.08±0.92)分、(4.38±1.01)分、(2.71±1.07)分、(3.66±1.30)分、(2.68±1.01)分、(2.95±1.04)分,均低于对照组的(3.84±0.51)分、(4.92±0.32)分、(3.87±0.47)分、(4.18±0.54)分、(3.82±0.38)分、(3.97±0.41)分,差异有统计学意义(均P<0.05)。研究组健康问卷抑郁量表(PHQ-9)与广泛性焦虑评定量表(GAD-7)评分分别为(16.35±5.88)分、(13.87±3.73)分,均高于对照组的(5.15±1.76)分、(5.89±1.39)分,差异有统计学意义(均P<0.05)。结论:女性生殖道感染以宫颈炎和非特异性阴道炎为主,生殖道感染会导致女性患者血清炎症因子水平显著升高,性功能降低,同时对患者心理状态也存在一定影响,因此,在临床工作中应予以患者及时有效的干预,从而改善患者性功能以及心理状态。

Objective:To understand the distribution of female reproductive tract infection types,and to analyze the influence of reproductive tract infection on female serum inflammatory factors,sexual function and psychological state.Methods:60 female patients with reproductive tract infections who were treated in our hospital from May 2016 to August 2018 were selected(study group),and 60 healthy women who came to our hospital for physical examination in the same period were selected(control group).The infection types of reproductive tract infection in the study group were analyzed,and the serum inflammatory factors,sexual function and mental state of the two groups were compared.Results:Cervicitis(33.33%)and nonspecific vaginitis(26.67%)were the most common types of infection in 60 patients with genital tract infection.The levels of serum tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and interleukin-8(IL-8)in the study group were respectively(144.38±31.85)ng/mL,(73.85±15.73)ng/mL,and(218.64±43.28)ng/mL,respectively,which were higher than(99.01±22.25)ng/mL,(40.27±10.52)ng/mL,(113.82±26.08)ng/mL in the control group,the difference was statistically significant(P<0.05).The scores of sexual desire,orgasm frequency,sexual satisfaction,sexual anxiety,spousal climax frequency and spousal satisfaction in the study group were respectively(3.08±0.92)scores,(4.38±1.01)scores,(2.71±1.07)scores,(3.66±1.30)scores,(2.68±1.01)scores,(2.95±1.04)scores,which were lower than(3.84±0.51)scores,(4.92±0.32)scores,(3.87±0.47)scores,(4.18±0.54)scores,(3.82±0.38)scores and(3.97±0.41)scores in the control group,the difference was statistically significant(P<0.05).The scores of Health Questionnaire depression scale(PHQ-9)and Generalized Anxiety Rating Scale(GAD-7)in the study group were respectively(16.35±5.88)scores and(13.87±3.73)scores,which were higher than(5.15±1.76)scores and(5.89±1.39)scores in the control group,the difference was statistically significant(P<0.05).Conclusion:Cervicitis and nonspecific vaginitis are the main types of female reproductive tract infection,genital tract infection can lead to a significant increase the levels of serum inflammatory factors and a decrease in sexual function in female patients,at the same time,it also has a certain influence on the patient’s psychological state,in clinical work,patients should be timely and effective intervention,so as to improve the patient’s sexual function and psychological state.