舍曲林联合绘画治疗青少年抑郁症疗效观察

Efficacy of Sertraline Hydrochloride Combined with Painting in the Treatment of Adolescent Depression

目的探讨舍曲林联合绘画治疗青少年抑郁症的疗效,以及对患者的抑郁症状、自我意识功能的改善作用。方法选取医院2019年5月至12月收治的青少年抑郁症患者42例,按盲法随机分为对照组(20例)和观察组(22例)。两组患者均予盐酸舍曲林治疗,观察组患者增加绘画治疗,均连续治疗8周。结果治疗4周、8周时,观察组患者的儿童抑郁障碍自评量表评分均显著低于对照组(P <0.01),儿童自我意识量表总分均显著高于对照组(P=0.001);治疗4周,观察组患者的躯体外貌与属性因子评分显著高于对照组(P <0.001);治疗8周,观察组患者的躯体外貌与属性因子、行为因子、智力与学校情况因子、焦虑因子评分均显著高于对照组(P <0.001);观察组与对照组患者的不良反应发生率相当(22.73%比30.00%,P> 0.05)。结论舍曲林联合绘画治疗青少年抑郁症疗效较好,可改善患者的抑郁症状,提高自我意识功能,且安全性较好。

Objective To investigate the efficacy of sertraline hydrochloride combined with painting in the treatment of adolescent depression,and its effect on the improvement of depression symptoms and self-awareness function. Methods A total of 42 patients with adolescent depression admitted to our hospital from May to December 2019 were selected and randomly divided into the control group( 20 cases) and the observation group( 22 cases) according to the blind method. The patients in the two groups were treated with sertraline hydrochloride,on this basis,the patients in the observation group were given painting therapy. Both groups were continuously treated for eight weeks. Results After four and eight weeks of treatment,the scores of children’s self-rating depression scale( SDS) in the observation group were significantly lower than those in the control group( P < 0. 01),and the total scores of children’s self-awareness scale in the observation group were significantly higher than those in the control group( P = 0. 001). After four weeks of treatment,the scores of physical appearance and attribute factors in the observation group were significantly higher than those in the control group( P < 0. 001). After eight weeks of treatment,the scores of physical appearance and attribute factors,behavior factors,intelligence and school status factors and anxiety factors in the observation group were significantly higher than those in the control group( P < 0. 001). The incidence of adverse reactions in the observation group was similar to that in the control group( 22. 73% vs.30. 00%,P > 0. 05). Conclusion Sertraline hydrochloride combined with painting is effective and safe in the treatment of adolescent depression,which can improve the depressive symptoms and the self-awareness function.