不规则抗体筛查对临床输血安全的价值研究

Research on the Value of Irregular Antibody Screening in Improving the Safety of Clinical Blood Transfusion

目的研究不规则抗体筛查对临床输血安全的价值和意义。方法回顾性分析2020年1—12月拟在我市输血但初配不顺利的355例患者临床资料,收集其详细资料及抗体筛查结果,以此分析不规则抗体筛查对提高输血安全性的价值和意义。结果(1)经筛查发现,350例患者为不规则抗体,其中190例为男性,160例为女性,阳性抗体的检出率约为98.59%。阳性与阴性数据差异具有统计学意义(P<0.05)。(2)在350例不规则抗体患者中,其中290例患者为Rh系统抗体阳性,73例患者为抗-E抗体阳性,抗-DC抗体阳性为70例,抗-D抗体阳性为72例,抗-e抗体阳性为75例,另外60例患者为MNS系统抗M抗体阳性。结论不规则抗体的检出率比较高,在实施输血治疗前应对受血者进行不规则抗体筛查,降低输血后不良反应,提高患者输血治疗的安全性。

Objective To study the value of irregular antibody screening in improving the safety of clinical blood transfusion.Methods The clinical data of 355 patients who planned to receive blood transfusion in Zhuhai from January to December 2020,but were not well matched at the beginning were retrospectively analyzed,and the detailed data and antibody screening results were collected to analyze the importance of irregular antibody screening for the safety of blood transfusion.Results(1)After screening,350 patients were found to have irregular antibodies,including 190 males and 160 females.The detection rate of positive antibodies was about 98.59%.The difference between positive and negative data was statistically significant(P<0.05).(2)Among 350 patients with irregular antibodies,290 patients were positive for Rh system antibody,73 patients were positive for anti-E antibody,70 patients were positive for anti-DC antibody,72 patients were positive for anti-D antibody,75 patients were positive for anti-e antibodies,and 60 patients were positive for MNS system anti-M antibodies.Conclusion The detection rate of irregular antibodies is relatively high,and irregular antibodies should be screened before blood transfusion treatment to reduce adverse reactions after blood transfusion and ensure the safety of patients with blood transfusion treatment.