痉挛型脑瘫执行功能损伤的MRI研究进展

Research Progress on MRI of Executive Function Injury of Spastic Cerebral Palsy

痉挛型脑瘫是胎儿或婴儿期大脑非进行性脑损伤导致肢体运动受限,肌张力持续性增高。脑室周围白质损伤(PWMI)作为新生儿最常见的脑损伤,是痉挛型脑瘫的主要发病原因。以往研究主要聚焦于PWMI所致痉挛型脑瘫运动功能障碍。然而,脑瘫常伴随高级认知过程-执行功能损伤。执行功能损伤对脑瘫的康复治疗、生活技能及生存质量产生重大影响。因此,本文就痉挛型脑瘫执行功能损伤的MRI研究进行综述,旨在为临床及时有效地干预及精准诊疗提供影像标记物,提高患儿生存质量,减轻家庭及社会的负担。

Spastic cerebral palsy is a non-progressive brain injury in the fetus or infant,resulting in limited limb movement and a continuous increase in muscle tone.Periventricular white matter injury(PWMI),as the most common brain injury in neonates,is the leading cause of spastic cerebral palsy.Previous studies mainly focused on the motor dysfunction of spastic cerebral palsy caused by PWMI.However cerebral palsy is often accompanied by impairment of higher cognitive process-executive function.The Injury of executive function can greatly influence rehabilitation treatment,life skills,and quality of life of cerebral palsy.Therefore,this paper reviews the MRI studies on the executive function of spastic cerebral palsy,aiming to provide imaging markers for timely and effective clinical intervention and accurate diagnosis and treatment,improve the quality of life of children,and reduce the burden on families and society.