空间小鼠实验有效载荷研究进展

Research Progress of Space Mice Flight Payload

啮齿动物是空间研究中常见的模型对象,已开展的空间生物实验中,小鼠表现出对飞行条件的有效适应.通过空间培养,研究者可对失重环境下小鼠的生理行为、骨骼和神经系统变化做进一步研究分析.本文对空间小鼠实验有效载荷的研究进展及其空间飞行实验进行了概述,为中国空间站上的小鼠培养箱设计提供参考.概述了地面小鼠培养技术和装置,为空间小鼠实验有效载荷设计提供地面对照;从实验研究内容和硬件系统设计两方面介绍了国际上已开展的空间小鼠实验,为中国空间生命科学研究和工程研制提供参考;对于中国发展空间小鼠实验有效载荷提出了建议.

Rodents represent one of the most important animal models in space biology experiments.Compared to other animals,the mice could better adapt to weightless conditions in space.Consequently,more and more researchers focus on the study of space mice flight payload.In the capsule,the mice would undergo a series of magical changes in the physiological behavior,the bone,and the nervous system.The experiments have shown that the research about these changes might contribute to the diagnostic of astronauts health,such as muscle atrophy.It is reported that many space mice experiments have been carried out abroad.However,China has not yet had sufficient research in this field.In order to address the problem,a large number of relevant literature were surveyed in this work.The development of various mice flight payloads and the content of the experiment were summarized in this paper.The specific contents are as follows.Firstly,the technology of mice culture on the ground was introduced,which gives a reference for the design of the flight payload.Then,five kinds of existing flight payloads abroad were discussed.Finally,the proposal for the development of domestic mice flight payload was proposed.