血清脂肪酶、淀粉酶、C反应蛋白联合检验对急性胰腺炎的早期诊断价值

Value of the combined test of serum lipase,amylase and C-reactive protein in early diagnosis of acute pancreatitis

目的探讨血清脂肪酶、淀粉酶、C反应蛋白联合检验在急性胰腺炎早期诊断中的应用价值。方法选取2017年1月至2019年12月在南阳市第二人民医院诊治处理的急性胰腺炎患者210例作为观察组,另选取同期非急性胰腺炎患者210例作为参照组。予以全部入选患者血清脂肪酶、淀粉酶、C反应蛋白联合检验处理。收集患者的临床诊治资料并对相关资料展开回顾性的整合分析,比较两组的检测结果以及不同检验方式(血清脂肪酶检验、淀粉酶检验、C反应蛋白水平检验以及血清脂肪酶、淀粉酶、C反应蛋白联合检验)的检验精准度与灵敏度。结果与参照组比较,观察组的血清脂肪酶、淀粉酶、C反应蛋白水平均明显增高(P<0.05)。相较于单一血清脂肪酶检验、淀粉酶检验及C反应蛋白水平检验,血清脂肪酶、淀粉酶、C反应蛋白联合检验方式的检验精准度与灵敏度均呈现明显的提升趋势(P<0.05)。结论血清脂肪酶、淀粉酶、C反应蛋白联合检验在急性胰腺炎早期诊断中的应用价值较为理想,有利于提升急性胰腺炎早期诊断的精准度及灵敏度,能够为患者的后续治疗提供科学、可靠的数据支持,对疾病的早期诊断及预后观察具有重要意义。

Objective To investigate the application value of combined detection of serum lipase,amylase and C-reactive protein in early diagnosis of acute pancreatitis.Methods A total of 210 patients with acute pancreatitis treated in Nanyang Second People’s Hospital from January 2017 to December 2019 were selected as the observation group,another 210 patients with non acute pancreatitis in the same period were selected as the control group.The serum lipase,amylase and C-reactive protein of all patients were tested.The clinical diagnosis and treatment data of the patients were collected and the related data were analyzed retrospectively.The test results and the test accuracy and sensitivity of different test methods(lipase test,amylase test,C-reactive protein level test and combined test of serum lipase,amylase and C-reactive protein)were compared between the two groups.Results Compared with the control group,the levels of serum lipase,amylase and C-reactive protein in the observation group were significantly increased(P<0.05).Compared with single serum lipase test,amylase test and C-reactive protein level test,the accuracy and sensitivity of combined test of serum lipase,amylase and C-reactive protein showed a significant improvement trend(P<0.05).Conclusions The combined detection of serum lipase,amylase and C-reactive protein has ideal application value in the early diagnosis of acute pancreatitis,which can improve the accuracy and sensitivity of early diagnosis of acute pancreatitis,provide scientific and reliable data support for the follow-up treatment of patients,and is of great significance for the early diagnosis and prognosis observation of the disease.