化瘀通络灸改善血管性痴呆患者焦虑抑郁症状临床研究

Clinical Study of Huayu Tongluo Moxibustion in Improving Anxiety and Depression in Patients with Vascular Dementia

目的:观察化瘀通络灸改善血管性痴呆患者焦虑抑郁症状的临床疗效。方法:选取本院收治的40例血管性痴呆患者为研究对象。采用随机数字表法将其分别纳入化瘀通络灸组20例、西药组20例。对比两组患者治疗后的抑郁焦虑症状改善状况。结果:化瘀通络灸组的总有效率为85%(17/20),西药组的总有效率为55%(11/20),两者差异有统计学意义(P<0.05);两组患者治疗后的HAMD、HAMA及GDS评分均下降,差异有统计学意义(P<0.05);治疗后化瘀通络灸组ADL评分上升,差异有统计学意义(P<0.05),西药组ADL评分治疗前后差异无统计学意义(P>0.05)。治疗后组间对比结果显示,化瘀通络灸组患者HAMD、HAMA及GDS下降幅度均明显大于西药组,差异有统计学意义(P<0.05),化瘀通络灸组患者ADL评分与西药组对比,差异有统计学意义(P<0.05)。结论:化瘀通络灸对于血管性痴呆患者的焦虑抑郁情绪有较好的改善作用,并能够提高患者的生活质量,且临床疗效优于盐酸多奈哌齐。

Objective:To observe the clinical effect of Huayu Tongluo moxibustion in improving anxiety and depression in patients with vascular dementia(VD).Methods:40 patients with VD were randomly divided into the Huaya group(n=20)and the western medication group(n=20).The improvements of depression and anxiety were compared between the two groups after the treatment.Results:The total effective rate was 80%in the Huaya Tongluo moxibustion group and 55%in the control group,there was statistical difference between the two groups(P<0.05).The scores of GDS,HAMA and HAMD were significantly decreased after the treatment compared to those before the treatment in the two groups(P<0.05).The ADL score was significantly increased after the treatment compared to that before the treatment in the Huaya Tongluo moxibustion group(P<0.05);however,there was no statistical difference in ADL score between before and after the treatment in the western medication group(P>0.05).The decreases of the scores of GDS,HAMA and GDS were more significant in Huayu Tongluo moxibustion group than those in the western medication group(P<0.05).There was statistical difference in ADL score between the two groups after the treatment(P<0.05).Conclusion:Huayu Tongluo moxibustion has a better effect on the improvements of anxiety and depression in patients with VD,and it can improve the life quality of the patients.The clinical effect of Huayu Tongluo moxibustion is better than that of Donepezil Hydrochloride.