摘要
高血压是导致心血管疾病发生的重要危险因素。高血压所致的心、脑、肾等靶器官损害的主要机制是血管发生了动脉僵硬、动脉粥样硬化、狭窄和闭塞。脉搏波传导速度(PWV)和踝肱指数(ABI)是评估动脉硬度的早期重要指标,也是亚临床靶器官损害的检测参数之一。本综述旨在探讨PWV和ABI对高血压患者动脉硬化的早期诊断,以利于指导高血压患者心血管疾病早期预防及治疗。
Hypertension is an important risk factor leading to the development of cardiovascular disease.The main mechanism of target organ damage such as the heart,the brain and the kidneys caused by hypertension is the occurrence of arterial stiffness,atherosclerosis,stenosis and occlusion in blood vessels.Pulse wave velocity and ankle-brachial index are early important indicators for assessing arterial stiffness and one of the detection parameters for subclinical target organ damage.The aim of this review is to investigate the early diagnosis of arteriosclerosis in hypertensive patients by pulse wave velocity and ankle-brachial index in order to guide the early prevention and treatment of cardiovascular disease in hypertensive patients.
作者
马明怡
惠红
张晓卉
MA Ming-yi;HUI Hong;ZHANG Xiao-hui(Department of Cardiology,First Affiliated Hospital,Harbin Medical University,Harbin 150001,Heilongjiang,China)
出处
《心脏杂志》
CAS
2021年第2期214-217,共4页
Chinese Heart Journal
基金
面向生物医药领域示范项目资助(2017YFB1401804)
黑龙江省自然科学基金项目资助(LH2020H034)
黑龙江省博士后出站启动金项目资助(LBH-Q18080)
哈尔滨医科大学附属第一医院院基金项目资助(2019M08)。