GPR35与乳腺癌发生发展关系的研究进展

Research progress on the relationship between GPR35 and the occurrence an d development of breast cancer

G蛋白偶联受体从被发现至今受到了人们的广泛关注。G蛋白偶联受体35(GPR35)是临床上新发现的一种G蛋白偶联受体。近年来,越来越多的研究结果证实以GPR35作为治疗靶点的疗法可在各类疾病的治疗中发挥重要的作用。在本文中,笔者主要是对GPR35的结构、信号通路、生理功能及其与乳腺癌发生发展关系等方面的研究进展进行综述。

G protein coupled receptor(GPRR)has attracted extensive attention since its discovery.G-protein-coupled receptor 35(GPR35)is a new G-protein-coupled receptor.In recent years,more and more research results have confirmed that GPR35 as a therapeutic target therapy can play an important role in the treatment of various diseases.In this paper,the author mainly reviews the research progress on the structure,signaling pathway,physiological function of GPR35 and its relationship with the occurrence and development of breast cancer.