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西地兰、托拉塞米联合静滴硝酸甘油在心力衰竭患者中的应用探讨 被引量:1

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摘要 目的探讨西地兰、托拉塞米联合静滴硝酸甘油在心力衰竭患者中的应用。方法回顾性分析,将2017年4月至2020年11月我院接受托拉塞米+硝酸甘油治疗的27例心力衰竭患者纳入对照组;将同期接受托拉塞米+硝酸甘油+西地兰治疗的33例心力衰竭患者纳入观察组。比较两组患者临床疗效、治疗前及治疗3d后血清氨基末端B型钠尿肽(NT-proBNP)、左室射血分数、不良反应情况。结果治疗3d后,观察组患者总有效率(93.94%)高于对照组(66.67%)(P<0.05);两组患者血清NT-proBNP水平低于治疗前,左室射血分数高于治疗前,观察组血清NT-proBNP水平低于对照组,左室射血分数高于对照组(P<0.05);治疗3d内,观察组不良反应发生率(21.21%)与对照组(11.11%)比较,差异无统计学意义(P>0.05)。结论西地兰、托拉塞米联合静滴硝酸甘油治疗心力衰竭,可显著降低患者血清NT-proBNP水平,改善心脏功能,安全性较好。
出处 《心血管病防治知识(学术版)》 2021年第4期23-25,共3页 Prevention and Treatment of Cardiovascular Disease
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