罕见P血型不合致反复流产1例

Spontaneous abortion caused by rare maternal-fetal P blood group incompatibility: a case report

目的旨在为反复流产的诊治提供新方向。方法回顾性分析1例反复流产患者的临床资料,该患者血型不规则抗体阳性,最终确定血型为p血型。考虑其反复流产与罕见血型关系密切,且已中期妊娠,胎盘低置,经多学科会诊后,制定预存式自体备血方案。结果该例患者引产过程顺利。结论排除常见流产原因后,产科医生要对孕妇的不规则抗体进行筛查,并为需要备血的稀有血型孕妇围生期备血提供建议,可行预存式自体备血作为出血紧急预案之一。

Objective To provide a new direction for the diagnosis and treatment of recurrent spontaneous abortion.Methods The clinical data of one patient with repeated abortion were retrospectively analyzed.The patient's blood type was finally confirmed to be the rare p blood type.Considering that the patient was in the second trimester and had low-implantating placenta,a pre-stored autologous blood preparation scheme was developed after multidisciplinary consultation.Results The induction of labor was successful in this case.Conclusion After excluding the common causes of abortion,obstetricians should screen pregnant women for irregular antibodies in blood,and also provide suggestions for perinatal blood preparation for rare blood group pregnant women.It is feasible to adopt pre-stored autologous blood preparation as one of the emergency transfusion pre-plans.