体外受精-胚胎移植助孕与自然受孕的分娩情况及新生儿结局分析

Delivery of in vitro fertilization-embryonic transplantation assisted conception and natural conception and neonatal outcomes analysis

目的探讨体外受精-胚胎移植(IVF-ET)受孕与自然受孕产妇的分娩情况及新生儿情况。方法回顾性分析2019年1~12月珠海市妇幼保健院收治的8318例产妇的临床资料及分娩新生儿信息,根据受孕方式分为试管组(孕妇523例,新生儿611例)和正常组(孕妇7795例,新生儿7911例)。比较两组分娩方式、分娩相关并发症及新生儿结局。结果试管组剖宫产发生率高于正常组,差异有统计学意义(P<0.05);试管组早产、前置胎盘、产后出血、子痫发生率均高于正常组,差异有统计学意义(P<0.05);两组难产率和胎膜早破发生率比较,差异无统计学意义(P>0.05);试管组的新生儿感染性肺炎及低出生体重发生率均高于正常组,差异有统计学意义(P<0.05)。结论IVF-ET助孕的产妇患者分娩并发症及新生儿并发症风险增高,增加剖宫产手术概率,应注意围生期护理,及时处理并发症。

Objective To investigate the birth of in vitro fertilization-embryonic transplantation(IVF-ET)assisted conception and natural conception and neonatal conditions.Methods A retrospective analysis was conducted on 8318 puerperae′s clinical data and delivery of newborns from January 2019 to December 2019 in our hospital.According to different conceptions,they were divided into a test tube group(523 cases of pregnant women,611 cases of neonates)and a normal group(7795 cases of pregnant women,7911 cases of neonates).The mode of delivery,complications associated with delivery,and neonatal outcomes were compared in the two groups.Results The incidence of cesarean section of the test tube group was higher than that in the normal group,and the difference was statistically significant(P<0.05).The incidence rates of premature birth,placenta previa,postpartum bleeding,and eclampsia in the test tube group were higher than those of the normal group,the differences were statistically significant(P<0.05).There were no statistically significant differences in the incidence rates of dystocia or premature rupture of fetal membranes between the two groups(P>0.05).The incidence rates of neonatal infectious pneumonia and low birth weight were higher than those of the normal group with statistical significance(P<0.05).Conclusion The risks of delivery-related complications and neonatal complications are increased in IVF-ET assisted conception,which increases the probability of cesarean section,should pay attention to perinatal care,and treat complications in time.