摘要
甘草酸作为甘草的主要活性成分,具有抗炎、抗病毒、镇咳祛痰、免疫调节等药理作用,近年来又陆续发现很多临床新用途,并且会对人和动物的细胞色素P_(450)产生影响。笔者对甘草酸的临床应用及其对细胞色素P_(450)的影响进行了整理分析,以期为临床合理使用甘草酸制剂提供参考。
Glycyrrhizic acid,as the main active ingredient of Glycyrrhiza,has anti-inflammatory,antiviral,antitussive,expectorant,immunomodulatory and other pharmacological effects.In recent years,many new clinical uses of glycyrrhizic acid have been found,and glycyrrhizic acid has an effect on human and animal cytochrome P_(450).This paper summarizes the clinical application of glycyrrhizic acid and its effect on cytochrome P_(450),providing reference for clinical rational use of glycyrrhizic acid preparation.
作者
毛俊
刘慧茹
王浩浩
金涌
孟祥云
Mao Jun;Liu Huiru;Wang Haohao;Jin Yong;Meng Xiangyun(Department of Pharmacy,The Second People's Hospital of Hefei,Hefei 230026,Anhui Province,China;Key Lab of Anti-inflammatory and Immune Medicine,Ministry of Education,School of Pharmacy,Anhui Medical University,Hefei 230032,Anhui Province,China)
出处
《中国基层医药》
CAS
2021年第5期797-800,共4页
Chinese Journal of Primary Medicine and Pharmacy
基金
安徽省自然科学基金项目(1808085MH284)
安徽省合肥市医学重点学科建设资助项目(合卫科教(2019)160)。
关键词
甘草酸
甘草
活性成分
药理作用
临床新用途
人
动物
细胞色素P_(450)
Glycyrrhizic acid
Glycyrrhiza
Active ingredients
Pharmacological action
New clinical use
Human
Animal
Cytochrome P_(450)
