头颈部鳞状细胞癌的研究进展

Research progress of head and neck squamous cell carcinoma

头颈部鳞状细胞癌(HNSCC)是全球第6大常见恶性肿瘤,男性发病率高于女性,主要包括口腔、口咽部、喉部及下咽部等多个部位的恶性肿瘤。HNSCC的发病率高、临床表现多变、预后差,给患者生活造成了严重影响,也为临床诊治HNSCC带来了极大的挑战,现对HNSCC的致病因素、发病机制、诊断及治疗方面的研究进展进行综述。

Head and neck squamous cell carcinoma(HNSCC)is the sixth most common malignant tumor in the word.The incidence of HNSCC in males is higher than that in females.It may appear in multiple parts of the body,mainly including malignant tumors in the oral cavity,nasal cavity,oropharynx,larynx and hypopharynx.Because of the high incidence,variable clinical manifestations and poor prognosis,NHSCC has caused serious impact on patients’lives,and also brought great challenges to clinicians in the diagnosis and treatment of HNSCC.The authors review the pathogenic factors,pathogenesis,diagnosis and treatment of HNSCC in this paper.