放疗中肿瘤实时监测与追踪技术的研究进展

Research progress on real-time tumor monitoring and tracking technology in radiotherapy

肿瘤的运动限制了放疗准确性的进一步提高。肿瘤位置的实时监测与追踪是提高肿瘤放疗精度的一种新兴技术。根据所使用的方法大致分为基于非辐射的系统和基于辐射的系统。前者有超声引导、磁共振引导、电磁追踪、光学影像引导、基于人工智能等技术,后者有千伏级、兆伏级X线成像系统和基于CT的引导系统等。本综述回顾了目前放疗中肿瘤实时监测与追踪技术的研究进展,包括各自优缺点以及目前在临床上的运用情况。

The motion of the tumor limits further improvement in the accuracy of radiotherapy.Real-time monitoring and tracking of tumor location is an emerging technology to improve the accuracy of tumor radiotherapy.According to the adopted methods,it can be broadly divided into non-radiation-based and radiation-based systems.The former system includes ultrasound guidance,nuclear magnetic resonance guidance,electromagnetic tracking,optical image guidance,artificial intelligence-based technologies,and the latter system consists of KV,MV-grade X-ray imaging system and CT-based guidance system.In this review,research progresses on real-time tumor monitoring and tracking technology in radiotherapy,respective advantages and disadvantages and current clinical application were summarized.