哮喘患者不同吸入方式的效能比较

Comparison of open airway inhalation and conventional inhalation in asthma patients

目的观察哮喘患者应用开放气道吸入方式与常规传统吸入方式的效能比较。方法纳入2019年4月至2019年9月于四川大学华西医院门诊诊断为哮喘并且仅使用同一种吸入制剂控制哮喘的患者为研究对象,按照患者门诊就诊顺序,采用随机数字1∶1将研究对象分为试验组和对照组。对照组患者采用常规传统方式使用吸入制剂,试验组患者采用开放气道吸入方式使用吸入制剂。用药3个月后比较两组患者哮喘控制情况、生活质量、两种不同方式使用吸入制剂的教学满意度。结果共纳入病例150例,脱落1例,有效病例149例,其中试验组75例,对照组74例。使用吸入制剂3个月后,试验组患者哮喘控制人数比例高于对照组,对吸入制剂使用方法的教学满意人数多于对照组,差异均有统计学意义(均P<0.05)。使用吸入制剂3个月后,两组患者生活质量评分均较使用前有所增加,且试验组增加分值多于对照组,差异有统计学意义(P<0.05)。结论哮喘患者应用开放气道吸入方式在哮喘控制、患者对吸入制剂使用方法满意情况及生活质量方面均优于常规传统吸入方式。

Objective To study and compare the effects of inhaled preparations with open airway and conventional inhaled preparation on asthma patients. Methods The patients diagnosed with asthma and treated with the same inhaled preparation only who visited the outpatient department of West China Hospital of Sichuan University, were selected as the study subjects from April to September, 2019. The subjects were divided into the test group and the control group according to random ratio 1∶1. The conventional inhaled preparations were used in the control group. The inhaled preparations with open airway were used in the test group. Asthma control, life quality and treatment satisfaction rate were compared between the two groups after 3 months. Results A total of 150 subjects were included and one case dropped-off, then 149 effective subjects were obtained in which 75 cases in the test group and 74 cases in the control group. After 3 months’ treatment of inhaled preparations, the proportion of effective asthma control patients in the test group was higher than that in the control group, and the number of patients satisfied with the treatment of inhaled preparations was higher than that in the control group, with statistically significant differences(all P<0.05). The life quality of patients in both groups was improved compared with baseline, and the difference was statistically significant(P<0.05). However, the increase of scores in the test group was more than that in the control group, and the difference was also statistically significant(P<0.05). Conclusion Inhaed preparations with open airway is superior to conventional inhaled preparation on asthma patients in asthma control, life quality and treatment satisfaction rate.